- Sacred 2 Fallen Angel
- Saint's Row
- Saint's Row 2
- Scene It Box Office Smash
- Sega Rally Revo
- SEGA Superstars Tennis
- Shadow Complex
- Shadowrun
- Shaun White Snowboarding
- Silent Hill: Homecoming
- SKATE
- SKATE 2
- SKATE 3
- Small Arms
- Smash Court Tennis 3
- Soldier of Fortune: Payback
- Sonic the Hedgehog
- Soulcalibur IV
- Spec Ops: The Line
- Spider-Man: Friend or Foe
- SpiderMan 3
- Split Second
- Star Trek: Legacy
- Star Wars: The Force Unleashed
- Star Wars: The Force Unleashed II
- Stormrise
- Stranglehold
- Street Fighter IV
- Stuntman: Ignition
- Superman Returns: The Videogame
- Supreme Commander
- Surf's Up
Publisher: Madman | Developer: Ascaron | Date: Out Now
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Publisher: Red - Ant | Developer: GasPowered | Date: TBA
Publisher: Ubisoft | Developer: Ubisoft | Date: Out Now
